The global Digital PCR (dPCR) and Real-time PCR (qPCR) market size to be valued at USD 8 billion by the end of 2025, growing at a CAGR of over 9% during the forecast period. The digital PCR market size is expected to grow at a CAGR of over 11.5% during the forecast period. The global digital PCR (dPCR) and the real-time PCR (qPCR) market is one of the dynamic and fast-growing segments in the diagnostic and life sciences industries. The dPCR and qPCR market is growing at a significant rate due to the rising incidence of infectious diseases and genetic disorders, continuous technological advancements in PCR technologies, the successful completion of the human genome project, and increasing R&D investments, funds, and grants as well as the increasing use of biomarker profiling for disease diagnostics. The surge in the growth can also be attributed to the growing prevalence/incidence of epidemics and pandemics such as the COVID-19 pandemic.
The introduction of automated analyzers with advanced connectivity, and high throughput, with reduced waiting time and portability, the increase in the accuracy of the devices with the usage of the PCR specific test kits, ability to perform the large volume of tests in a shorter duration of time are expected to influence the market. Moreover, continued efforts by manufacturers to develop novel dPCR and qPCR systems and kits to use in molecular testing are likely to further propel the growth of the dPCR and qPCR market. New systems are expected to offer highly automated workflows and quick turnaround times than the current digital PCR platforms, which are likely to provide a significant competitive advantage.
- The digital PCR segment is expected to grow at a CAGR of over 11.5% during the forecast period as dPCRs are increasingly replacing real-time PCRs in the human genome project.
- The consumable segment is likely to reach a revenue share of close to $6 billion by 2025 due to the recurring usage of consumables for performing PCR tests.
- The clinical end-user segment is projected to observe an incremental growth of close to $1.8 billion by 2025 on account of the effective detection of bacteria by real-time PCR assays.
- The diagnostic segment is expected to grow at the highest CAGR of 10% during the period 2019–2025 due to the widespread application of PCR assays in diagnostic laboratories.
- The APAC region is likely to register the fastest CAGR of over 11% during the period 2019–2025 because of increased government support, awareness of advanced, accurate diagnosis PCR assays, and the high prevalence of infectious diseases.
GLOBAL dPCR AND qPCR MARKET SEGMENTATION
This research report market includes a detailed segmentation by
INSIGHTS BY TECHNOLOGY
In 2019, the Real-time PCR (qPCR) segment dominated the market and accounted for a share of over 90%. One of the major reasons for the dominance of qPCRs is that they are widely used in infectious disease diagnosis and research projects. Real-time PCRs (qPCRs) have been well-established as credible and capable technology and are relied upon by researchers for their speed, sensitivity, specificity, and convenience. Several laboratories in developing countries are upgraded their infrastructure and technical training to perform PCR-based diagnosis for infectious diseases, thereby driving the segment growth.
The Digital PCR (dPCR) segment is slowly gaining momentum in the market and dPCRs are accepted as an advanced technology among researchers. dPCRs are replacing qPCR in the human genome project and other sequencing studies and ongoing cancer research. In the current scenario, both of these technologies play a vital role in the market. PCR technologies as a whole – real-time and digital – show significant promise for driving growth in the future. While qPCR products continue to serve a real purpose in research labs, dPCR impressive levels of sensitivity, precision, robustness, and reproducibility are helping researchers propel their work beyond previous limits.
INSIGHTS BY PRODUCT
The usage of a wide array of several standard reagents and test kits to perform several PCR-based tests is a major factor responsible for the growth of the consumable segment. The usage of consumables is reoccurring in nature, which is generating continuous revenue for vendors. Therefore, several renowned vendors are manufacturing consumables for PCR instruments. In recent years, the demand for consumables is increasing at a significant rate; hence, vendors are offering a wide array of reagents and other associated consumables to perform a range of procedures. Both global and local/regional players are offering a diverse range of consumables catering to the end-users requirements. The high prevalence of several infectious diseases across the globe has increased the demand for PCRs.
The instrument segment includes both Digital PCR (dPCR) and Real-time PCR (qPCR), which are used to perform multiple tests in pharma and biotech, research labs, diagnostic labs, academic institutes, etc. As the demand for instruments is growing, vendors are coming with several new technologies, which offer connectivity, remote access, portability, automation. As the life span of analyzers and other equipment is higher, they do not require repetitive purchase. Vendors consider them as a one-time investment from end-users. The sale of the latest instruments/analyzers is higher in developed countries than in developing and underdeveloping countries. Several emerging economies such as China, India, Brazil are observing a high uptake of diagnostics equipment such as PCR, which is likely to influence the market segment.
INSIGHTS BY APPLICATION
The clinical end-user segment dominates the market as PCRs play a significant role in the detection of DNA methylation, recognition of viruses and protozoa in infectious diseases, estimation of gene copy number aberrations, and primer extension. The application of qPCR is high in the clinical application end-user segment due to the high cost of dPCR. As real-time PCR assays offer immediate results for the detection of bacteria, clinicians can confirm the infection status of the patient more rapidly than culture methods, allowing more specific and timely administration of appropriate therapy. The research application segment is limited to users in developed countries. The segment accounted for a share of over 44% in the global dPCR and qPCR market. Gene expression, genotyping, sequencing cloning, mutagenesis, and methylation are the major applications for PCRs in the research segment.
INSIGHTS BY END-USER
Diagnostic laboratories are the largest end-user of PCR instruments and consumables than other segments. They use PCR instruments for diagnosis purposes. Commercial and public health laboratories prefer the latest diagnostic equipment. Their investment focuses on advanced equipment for accurate results to attract customers. Private laboratories have expanded their footprints, especially in developing countries, which has stimulated the growth prospects. Moreover, the demand for standalone reference laboratories is growing gradually owing to the prevalence of pandemic conditions, or the outbreak of unexpected infectious diseases, requiring immediate diagnosis of the diseases for the large population in a shorter period.
In 2019, the hospital segment accounted for a share of over 23% in the global dPCR and qPCR market. Laboratories are the exclusive units in hospitals. Around 92% of hospitals operate with their own laboratories. They are one of the largest end-users of PCR instruments and consumables as these settings perform a wide range of diagnostics testing. The availability of skilled healthcare professionals with knowledge and expertise in treating and diagnosing such conditions also attract more patients to hospitals than other healthcare settings, thereby influencing the digital PCR and real-time PCR market share.
INSIGHTS BY GEOGRAPHY
In 2019, North America accounted for a market share of 45% of the global digital PCR (dPCR) and real-time PCR (qPCR) market. Several factors are responsible for the growth of the market in the region. However, the increase in the target population and the high incidence of several infectious disease diagnostics are driving the PCR demand. There has been increasing in the prevalence of sexually transmitted diseases in North America. In 2018, over 37,832 people were confirmed HIV positive in the US and other states. A significant increase in several infectious diseases such as hepatitis, TB, and HIV was reported in the US alone. Approximately every 3 minutes, one person in the US is diagnosed with blood cancer. An estimated 176,200 people in the United States are diagnosed with leukemia, lymphoma, or myeloma in 2019. The government expenditure on clinical diagnostics & laboratory services has grown by 3% during the period 2010–2017, reaching $96.6 billion. Advances in technology are likely to increase the role of PCR tests in detecting, treating, and monitoring diseases. PCR is widely used in hospital setups as the conventional technique of culture-based disease diagnosis requires long isolation time and hospital admission.
INSIGHTS BY VENDORS
The global Digital PCR (dPCR) and Real-time PCR (qPCR) market is highly dynamic with the presence of global, regional, and local players, offering a diverse range of analyzers, software, and reagents for end-users. Agilent Technologies, Bio-Rad Laboratories, Danaher, F. Hoffmann-La Roche, QIAGEN, Takara Biotech, and Thermo Fisher Scientific are the key players operating in the global dPCR and qPCR market. Global players are focusing on developing innovative products and expanding their product portfolio to remain competitive in the market. They are investing extensively in R&D and product development activities to expand their product portfolio. Manufacturers are continuously focusing on product launches & development and offering PCR instruments and software with new features to increase their market presence.
Vendors are focusing on developing and commercializing innovative analyzers, dPCR, COVID-19 PCR rapid test kits, and consumables to remain competitive and gain a significant presence in the market. New product approvals/launches coupled with R&D activities help vendors to expand their presence, enhance market growth during the forecast period, and sustain their market position in the global qPCR and dPCR market.
The Digital PCR (dPCR) and Real-time PCR (qPCR) market research report include in-depth coverage of the industry analysis with revenue and forecast insights for the following segments:
- Systems/Analyzers & Software
- Real-Time PCR
- Digital PCR
- Diagnostic Laboratories
- Research Laboratories
- Pharma & Biotech Companies
- Forensic Laboratories
- North America
- Asia Pacific
- South Korea
- Latin America
- Middle East & Africa
- South Africa
- Saudi Arabia