The global single-use bioprocessing market size to cross USD 7 billion by 2024, growing at a CAGR of over 14% during the forecast period. The increasing number of clinical research and pre-commercial drug development activities is propelling the growth of the global single-use bioprocessing market. SUB refers to the usage of vessels, equipment, conduits, and other active consumables that come into contact with process fluids only once and are then discarded after the usage. These units offer various advantages include low-capital expenditure, reduced risk of cross-contamination, and flexibility to meet changing consumer needs. The introduction of products as bioreactors, fermenters, filling and tubing systems, and filters are revolutionizing the biopharmaceutical industry. Chromatography systems, pumps, cell culture apparatus, and mixing systems are widely used across the biopharmaceutical manufacturing industry. The growing popularity of in-vitro diagnostic and therapeutic and the commercial scale production of antibodies are the major factors contributing to the growth. The increasing availability of single-use bioreactors, connectors, mixers, and bioprocessing containers, sampling and transfer systems, sensors single-use pumps, and other SUB products is boosting revenues. The growing demand for these products is leading to the introduction of innovative systems such as chromatography columns and membrane adsorbers. Leading pharma and biotech companies such as AbbVie, Baxter, Boehringer Ingelheim, Hoffmann-La Roche, Merck Serono, Novartis, Teva Pharmaceutical Industries, Sanofi, and Pfizer and CMOs such as Catalent, Patheon, Lonza, and Rentschler Biopharma are adopting these products in the market. Arizton’s research analysts estimate that the rise in production of high-volume pharmaceuticals in commercial quantity will positively impact the global single-use bioprocessing market.
The growing adoption of disposable equipment and accessories to manufacturing biopharmaceuticals, such as vaccines, monoclonal antibodies, and other biologics will encourage consumers to launch a wide range of products. Also, increasing number of researches on cell therapies, vaccines, biosimilars, stem cells, and gene therapy will propel the demand in the market.
The high uptake of biopharmaceuticals and biosimilars and the growing penetration of biologics such as mAbs, cell therapies, and vaccines are driving the growth of the global single-use bioprocessing market. The introduction of new biologics and rise in adoption across developed nations is augmenting the development of the global market. The introduction of innovative immunotherapy antibodies such as Keytruda (pembrolizumab), Opdivo (nivolumab), and CAR-T cell therapies that tackle diseases such as cancer and autoimmune diseases is expected to boost the requirement of these products. The rising number of R&D activities across the pharma industry and growing importance and the acceptance of biopharmaceutical drug molecules are expected to boost sales over the next few years. Vendors are investing in R&D of biosimilars to capitalize on these multi-billion-dollar opportunities in the market.
SINGLE-USE BIOPROCESSING MARKET SEGMENTATION
This research report includes a detailed segmentation by
INSIGHTS BY PRODUCT
The rise in drug development and clinical research boosts investments in single-use products
The product segment is segmented into simple & peripheral devices and single-use bioprocessing equipment. Single-use processing equipment dominated more than half of the total market share in 2018, growing at a CAGR of over 16% during the forecast period. The increasing focus on innovation, evolution, and adoption of next-generation technology is augmenting the growth of this segment. The shift from using reusable techniques to disposable products for applications such as media preparation and storage, buffer preparation, cell harvesting fermentation, and purification will contribute to the revenues in this segment. The reduction in contamination, cost-effectiveness, higher product efficiency, and reduced time-to-market of SUBs is fueling the adoption of these products. The introduction of equipment that offers a combination of control automation, hardware, and single-use assemblies will revolutionize the global single-use bioprocessing market.
INSIGHTS BY APPLICATION
Establishment of hybrid manufacturing facilities will drive the need for purification applications
The application segment is classified into filtration, storage & transfer, cell culture, mixing, and purification. Purification is the fastest growing segment, at a CAGR of around 20% during the forecast period. The rise in the usage of these technologies in downstream processing and high demand for establishing hybrid manufacturing facilities to optimize the productivity and yield of biopharmaceuticals fully is contributing to the growth of this segment. The vendors are focusing on developing innovative products for purification that includes chromatography systems, membrane adsorbers, and associated devices to attract a maximum number of consumers. These systems are designed with features such as higher capacity, superior sensitivity and accuracy, and shorter process time. The development of membrane adsorbers that are ready-to-use and save time by eliminating cleaning, packing, and revalidation steps during downstream processing will transform the global single-use bioprocessing market.
The introduction of disposable filtration devices features high-efficiency membrane components that allow high-temperature metabolic reactions to flow smoothly will boost sales. The adoption of this solution for scale-up cell culture applications in clinical trials, process development, and large-scale cGMP biomanufacturing will positively impact the global market.
INSIGHTS BY END-USERS
Stringent quality requirements will boost adoption of these products by biopharmaceutical companies
The end-user segment is categorized into biopharmaceuticals manufacturing companies, CMOs, and R&D companies & research institutes. Biopharmaceutical manufacturing companies occupied more than 1/3rd of the total market share in 2018, growing at a CAGR of approximately 13% during the forecast period. The high uptake of biopharmaceuticals and biosimilars worldwide is encouraging biologic manufacturers to use disposable products. Companies like Amgen, Boehringer Ingelheim, Bristol-Myers Squibb, Eli Lilly, Novartis, Pfizer, Regeneron, and Sanofi are investing in the enhancement of biomanufacturing capabilities and single-use technologies in the global market. The global single-use bioprocessing market is expected to witness an increase in sales of targeted therapies, personalized medicine, regenerative medicine, and antibody–drug conjugates during the forecast period.
The rise in the number of new drug entities that are in various pre-clinical and clinical phases of development will boost the adoption of single-use products in the CMO sector in the global market. The growing number of healthcare R&D companies and research institutes will propel the growth of the global market.
INSIGHTS BY GEOGRAPHY
Improved R&D infrastructure across APAC will contribute to the revenues in the global single-use bioprocessing market shares
The geographical segment is divided into North America, Europe, APAC, Latin America, and Middle East & Africa. APAC is the fastest growing region, at a CAGR of about 18% during the forecast period. The rising demand for pre-fabricated and cost-effective modular facilities is augmenting the growth of the APAC region. The improving R&D infrastructure, rapid business expansion plans of global players, and increasing government initiatives are some of the factors attributing to the growth of the APAC region. Countries such as Japan, China, South Korea, Australia, and India recognized the benefits of SUTs, such as cost-effectiveness, pre-validation of systems, and quick set-up, thereby, contributing to the revenues in the global single-use bioprocessing market shares. Also, high uptake of biosimilars, lower labor costs, and low operating costs are encouraging vendors to expand their businesses to APAC region.
The growing adoption of disposables (simple and peripheral devices) and highly advanced systems such as mixing systems, bioreactors, and cell culture systems is driving the growth of the North American region. Germany, France, and the UK are major revenue generators across the European region.
INSIGHTS BY VENDORS
The global market is highly dynamic and offers significant growth opportunities for vendors. The leading players are investing in the development and launch of a broad range of SUTs to sustain the intense competition. The acquisition of emerging/small, specialized single-use suppliers, development of product portfolio, expansion in regional markets, and strengthening of global distribution networks are strategies adopted by manufacturers to gain a larger market share. The top vendors are expanding their businesses to emerging nations to gain a competitive advantage.
Major vendors in the market are Thermo Fisher Scientific, Sartorius Stedim Biotech, Merck KGaA, Danaher, GE Healthcare, and Avantor.
The single-use bioprocessing market research report includes in-depth coverage of the industry analysis with revenue and forecast insights for the following segments:
Segmentation by Product
- Simple & Peripheral Devices
- Single-Use Bioprocessing Equipment
- Storage & Transfer
- Cell Culture
- Biopharmaceuticals Manufacturing Companies
- R&D Companies & Research Institutes
- North America
- Latin America
- Middle East & Africa