Liquid Handling System Market Size by Product, by Method, by Application, by End-User, & Geographical Analysis, Growth, Insights, Forecast 2021-2030

Global Liquid Handling System Market - Focused Insights 2021-2030

LIQUID HANDLING SYSTEM MARKET SIZE

The global liquid handling system market was valued at USD 4.34 billion in 2024 and is expected to reach USD 6.75 billion by 2030, growing at a CAGR of 7.64% during the forecast period. The market is evolving rapidly, driven by the rising clinical research and development activities, clinical trials, rising demand for clinical diagnostics, and growing lab automation are some of the major factors creating significant demand for liquid handling systems.  

Furthermore, this surge in growth is attributed to the growing advancement and integration of new technology. Robotics, automation, and the incorporation of Artificial Intelligence and machine learning technologies in liquid handling systems are expected to deliver lucrative market growth opportunities.

KEY TAKEAWAYS

1. Market Growth: The global liquid handling systems market size was valued at USD 4.34 billion in 2024 and is expected to reach USD 6.75 billion by 2030, growing at a CAGR of 7.64% during the forecast period.
2. By Product: In 2024, the pipettes segment accounted for the largest market share of over 28%.
3. By Method: The manual segment shows the highest growth of 8.75% during the forecast period.
4. By Application: The drug discovery & development segment holds the largest market share.
5. By End-User: In 2024, the pharma & biotech companies will dominate the market share.
6. By Geography: North America is the most dominant region for the liquid handling system market, accounting for around 30% of the share.
7. Growth Factor: The global liquid handling systems market is set to grow due to the growing importance of lab automation and automated liquid handling systems and the importance of liquid handling in drug discovery & development.

RECENT VENDORS ACTIVITIES

1. In 2024, Hamilton, one of the global manufacturers of automated liquid handling systems, launched its latest innovation, ZEUS X1 (Z- Excursion Universal Sampler = eXchange Series 1ml) combines the company’s advanced Compressed O-Ring Expansion (CO-RE II) technology with air displacement pipetting technology.
2. In 2024, Eppendorf, one of the leading companies in the life sciences industry, launched the Enhance Feature Set GxP software extension for its epMotion automated liquid handling systems.
3. In 2023, Scientific Laboratory Suppliers, one of the major distributors of laboratory solutions, launched Eppendorf’s epMotion Series for Automated Liquid Handling Systems.
4. In 2023, Revvity launched a next-generation Fontus Automated Liquid Handling Workstation, incorporating the advanced technologies from the company’s existing platforms to deliver faster and easier workflow for next-generation sequencing (NGS) as well as diagnostic research applications.
5. In 2023, Agilent Technologies, one of the leading market players, released the Agilent Bravo NGS automated liquid handling platform with an On-deck Thermal Cycler (OTDC) accessory that enables the ALH system to provide thermal cycling as a part of automated workflow for NGS, cell-based applications, and Polymerase Chain Reactions (PCR).

LIQUID HANDLING SYSTEMS MARKET TRENDS & DRIVERS

Transformation of Liquid Handling Systems in Genomics

The transformation in liquid handling systems from imprecise and hazardous methods of mouth pipetting in the early 20th century to the introduction of the first air-displacement mechanical pipette in the 1950s significantly revolutionized the genomics field, and now it has become a major field contributing to health revenue for market growth. Furthermore, the development of advanced semi-automated to fully-automated liquid handling systems, tremendously transformed genomics research by offering a higher level of precision, safety, and efficiency that keeps pace with rapid advancements in genomics. According to SPT Labtech (2023), one of the market players stated that advancements in liquid handling systems empower researchers and scientists in the genomic revolution. One of the key technologies that transform genomics is Next-generation Sequencing (NGS), which enables scientists to obtain sequencing data at a lower cost and on a higher scale than ever before.

Advancements in Microplate Reagent Dispensers for Liquid Handling Systems

Microplate reagent Dispensers have become technology-driven tools in liquid handling, enabling precise, automated, and versatile liquid handling for a range of diverse applications in life sciences industries. The growing integration capabilities of robotics and automation systems and the incorporation of technology-driven tools and commands make them one of the most reliable automated tools in liquid handling. There are Several market players advancing microplate reagent dispensing to stand out as unique in the market. For instance, BioTek’s range of microplate washers and dispensers can integrate with several robotic systems for increased efficiency and automation. It’s one of Multimode Dispenser – BioTEk MultiFlo FX for 6-to 1536-well microplate systems incorporates several unique technologies, such as patented automated media exchange (AMX) modules, random access dispense (RAD), and parallel dispense modules.

Importance of Liquid Handling in Drug Discovery & Development

Liquid Handling System is the most essential equipment in several aspects of drug discovery and development (DDD), involved in almost every stage. Increasing attention to liquid handling quality assurance early in the DDD processes is the most recognized way that biopharma companies can enhance efficiency and quality in their regular operations. By incorporating the Liquid Handling Quality Assurance (LHQA) program from compound preparation through clinical studies, biopharma companies’ labs can develop quality into their clinical trials processes and decrease the time and cost of drug discovery. As of 2025, more than 40 to 55 drugs are launched annually, and over 10,000 new drug compounds are in the pipeline globally, according to the International Federation of Pharmaceutical Manufacturers and Associations report 2023. The growing clinical studies and increasing demand for liquid handling procedures are accelerating a significant demand for liquid handling systems.

Growing Importance of Lab Automation and Automated Liquid Handling Systems

Worldwide, the COVID-19 pandemic significantly influenced the adoption of lab automation and liquid handling automation due to the global shift towards remote work in laboratories. In addition, in the post-pandemic period, the associated benefits, such as significant precision in liquid handling, minimized material wastage, high accuracy, and cost efficiency, are some of the factors that significantly increase attention towards lab automation and automated liquid handling systems. Gilson Incorporated, one of the leading market players in liquid handling systems, reported that the demand and deployment of automated liquid handling systems have significantly accelerated since the start of the COVID-19 pandemic.

LIQUID HANDLING SYSTEMS MARKET SEGMENTATION INSIGHTS

INSIGHTS BY PRODUCT

The global liquid handling systems market by product is segmented into pipettes, automated liquid handling systems, microplate reagent dispensers, burettes, and others. In 2024, the pipettes segment accounted for the largest market share of over 28%. Pipettes are among the most commonly used laboratory tools across various types of labs, designed to handle liquid materials with precision while ensuring the safety of lab personnel. Scientists, researchers, lab technicians, and students alike rely heavily on pipettes to accurately measure and dispense liquid samples. Advanced pipettes are now widely available in both single- and multi-channel formats, offering accuracy rates within 3% of the specified volume. Volumetric pipettes, often regarded as the gold standard for precision and accuracy, are frequently used by researchers studying chemical reactions and properties. Their broad application in biopharmaceutical companies and general scientific laboratories is driving significant demand, as they help streamline lab operations. Moreover, advancements in technology, such as the integration of automation and robotics, are further accelerating pipette adoption.

INSIGHTS BY METHOD

The global liquid handling systems market by method is categorized into electronic, automated, and manual. The manual segment shows significant growth, with the fastest-growing CAGR of 8.75% during the forecast period. Manual liquid handling methods offer a cost-effective and efficient approach, utilizing limited resources and relying on human operation for tasks such as dispensing and pipetting. Common tools include manual pipettes, micropipettes, and bottle-top dispensers. Key factors driving the adoption of manual methods include affordability, ease of access, and minimal training requirements. These methods are widely used across scientific, clinical, and research laboratories, contributing to increasing demand and segmental expansion. Additionally, a growing number of academic institutions, as well as small and medium-sized laboratories, are emerging as key consumers of manual liquid handling systems.

INSIGHTS BY APPLICATION

Based on the application, the drug discovery & development segment dominates and holds the largest global liquid handling systems market share. The application of liquid handling systems is rapidly expanding within the drug discovery sector. With thousands of clinical studies and trials in development or in the pipeline, there is a growing need for precise and efficient liquid handling solutions. Modern advancements in these systems—including automation, robotics, and the integration of technologies such as artificial intelligence (AI), machine learning (ML), and cloud computing—enable scientists and researchers to explore molecular processes with greater precision and speed. Liquid handling tools offer key benefits, such as cost and time savings, reduced human error, and minimized material waste, effectively addressing critical challenges in drug discovery. Globally, the rising demand for advanced medicinal products continues to drive the adoption of liquid handling systems in research and development.

INSIGHTS BY END-USER

Based on end-user segmentation, pharmaceutical and biotechnology companies hold the largest share of the global liquid handling systems market. This dominance is driven by increasing R&D activities, a growing number of clinical trials, and a rising focus on personalized medicine development. Biopharma companies are making substantial investments in clinical research and pharmaceutical manufacturing, where liquid handling systems—particularly for pipetting and fluid dispensing—are essential for ensuring operational efficiency and precision. The global demand for advanced therapies has fueled the development and production of biological drugs, including vaccines, monoclonal antibodies, cell and gene therapies (CGTs), growth factors, interferons, recombinant hormones, and more. In these applications, automated liquid handling (ALH) systems are gaining popularity due to their high-throughput capabilities and rapid processing. As pharmaceutical and biotech firms manage thousands of clinical tests and sample-handling operations, the need to reduce manual labor and associated risks has led to a growing reliance on liquid handling systems.

GEOGRAPHICAL ANALYSIS

North America is the leading region in the global liquid handling systems market, accounting for around 30% of the total market share. The demand for liquid handling systems is higher in North America compared to other regions, primarily due to the strong presence of numerous biotech and pharmaceutical companies, along with their dedicated research labs and hubs. Additionally, the region is home to many high-tech academic institutions engaged in advanced research, further driving demand for liquid handling solutions. North America hosts a wide range of small, medium, and large market players that actively promote liquid handling equipment, software, and tools for clinical diagnostics, biopharmaceutical R&D, and academic research. Both the U.S. and Canada are witnessing a surge in healthcare R&D activities, significant growth in clinical and research laboratories, and increasing adoption of automation and robotics. Moreover, North America accounts for the highest expenditure on clinical research globally, reinforcing its leadership in the liquid handling systems market.

VENDOR LANDSCAPE

The global liquid handling systems market report consists of exclusive data on 39 vendors. Agilent Technologies, Danaher, Eppendorf, Corning Incorporate, METTLER TOLEDO, Thermo Fisher Scientific, and Tecan Trading AG are some of the leading companies that accounted for the highest market share in the global liquid handling systems market. These vendors offer high-class and advanced liquid handling systems that meet customers’ requirements as well as comply with regulatory authorization standards. Major market players are increasing the efficiency of their products and strengthening their market position. These companies have a strong brand image and a wide geographical reach across the global market. Also, the adoption of various strategies, such as product launches, and new product development with advanced technologies and materials and technologies has intensified the competition in the market. The adoption of such strategies by the vendors and their focus on expanding their capabilities have enabled them to gain a higher revenue share in the market.