THE U.S. ONLINE PHARMACY MARKET SIZE TO REACH USD 146 BILLION IN 2026, GROWING AT A CAGR OF 19% DURING THE FORECAST PERIOD

U.S. Online Pharmacy Market Size, Share, Trends Analysis Report by Drug Type (Prescription and OTC); Product (Medication, Health Wellness & Nutrition, Personal Care & Essentials, and Others); Modality (Mobile Application and Website); Pharmacy Type (Online branch of Brick and Mortar, Independent Online Only Pharmacies, and Partnerships with Neighborhood Pharmacies); and Geography (US), Industry Analysis Report, Regional Outlook, Growth Potential, Price Trends, Competitive Market Share & Forecast, 2021–2026

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Most Exhaustive Report

152 Pages

13 Tables

72 Charts

1 Regions

1 Countries

30 Companies

4 Market Segment

U.S. ONLINE PHARMACY MARKET REPORT SCOPE

Report Attribute Details
MARKET SIZE (REVENUE) USD 146 BILLION (2026)
CAGR 19% (2021-2026)
Base Year 2020
Forecast Year 2021–2026
Market Segments Drug Type (Prescription and OTC), Product (Medication, Health Wellness & Nutrition, Personal Care & Essentials, and Others), Modality (Mobile Application and Website), Pharmacy Type (Online branch of Brick and Mortar, Independent Online Only Pharmacies, and Partnerships with Neighborhood Pharmacies)
Geographic Analysis United States
Countries Covered US

U.S ONLINE PHARMACY INDUSTRY INSIGHTS

The U.S. online pharmacy market size was valued at USD 52 billion and is expected to reach USD 146 billion in 2026, growing at a CAGR of 19% during 2020-2026. The US e-pharmacy industry has gained momentum with the increasing use of e-prescription by hospitals and the high penetration of the internet and smartphones.

Automated prescription filling, automated customer relationship management, direct-to-the-patient sales of medicines are other major factors increasing the adoption of online pharmacies across the US. The market is shifting toward the direct-to-patient model as the ever-expanding digital world opens doors to new services and consumer-friendly online experiences. The ease and familiarity of online purchasing attract several patients to search for virtual care medications and wellness options. This has increased online pharmacies to advertise more and acquire more consumers through digital platforms. The COVID-19 pandemic has further accelerated this shift as most healthcare professionals and patients have adapted to the virtual way to purchase medicines. The trend expects to increase drastically across North America post-COVID-19.

SNIPPETS

  • The prescription-based online pharmacy market will likely observe an incremental growth of over USD 85 billion by 2026.
  • The high prevalence of chronic diseases such as diabetes, cancer, hypertension, and cardiovascular disorders is likely to aid the growth of the medication segment, growing at a CAGR of over 18% from 2020 to 2026.
  • The online health wellness and nutrition pharmacy market is likely to grow at the highest CAGR of over 23% from 2020 to 2026 due to increased vitamins, minerals, and nutrients supplements among US consumers.
  • The mobile application segment expects to reach over USD 107 billion by 2026 due to the high popularity of smartphones, especially among millennials.
  • Independent online pharmacies are expected to grow at the fastest CAGR from 2020 to 2026 due to cost efficiency and reimbursement facilities.

U.S. ONLINE PHARMACY MARKET SEGMENTATION

This research report includes a detailed segmentation by

  • Drug Type
  • Product
  • Modality
  • Pharmacy Type

INSIGHTS BY DRUG TYPE 

The prescription-based US online pharmacy market is likely to cross USD 132 billion by 2026. A significant factor driving the growth of prescription-based medicines via online mode is cost-efficiency. Consumers prefer to purchase drugs from online stores as they offer medications at a low price than retail outlets. Among US adults prescription-taking medications, 1.5% reported having purchased medicines outside the US due to high costs. Hence, online pharmacies are seen as the best solution for providing prescription medications at discounted prices, thereby observing growth.

The OTC market accounted for the share of approx. 11% in the US pharmacy market. The usage of OTC medicines has been increasing over the years. According to the Consumer Healthcare Products Association, 81% of adults in the US use OTC medicines to treat several minor illnesses. OTC drugs are comparatively cheaper than prescription drugs. Over 25% of OTC sales currently occur online in the US. The demand for OTC medicines is increasing partially due to growing prescription drug costs. There is an increased number of new private labels that are likely to be introduced in the market.

INSIGHTS BY PRODUCT

In 2020, the medication segment accounted for approx. 76% in the U.S. online pharmacy market share. The increase in the patient population along with the increased geriatric population is increasing the demand for medications. There is an increase in consumers preferring online pharmacy platforms to purchase medicines due to high purchase convenience. Many customers and patients prefer using online pharmacies for refilling long-term medications.

The US online health wellness and nutrition segment expect to reach over USD 26 billion by 2026. Over the years, there has been a significant change in consumer behavior concerning health, wellness and nutrition products. Most US population aspiring to have a healthy lifestyle use fitness applications and are willing to pay a premium for health. In 2019, over 68 million smartphone owners in the US used at least one health or fitness application once per month. The COVID-19 pandemic further accelerates this trend. Pandemic has impacted the importance of good health and immunity to fight illness. Since the COVID-19 pandemic has affected the US considerably, consumers have increasingly turned toward vitamins, minerals, and nutrients supplement (VMS) products, expressing more significant interest in and engagement with the category.

INSIGHTS BY MODALITY

The mobile app-based segment will likely grow at a CAGR of over 19% from 2020 to 2026. Mobile applications play a significant role in the global online pharmacy market. They help online pharmacies to get in touch with consumers directly, thereby increasing the patient base. Mobile applications help online pharmacies to position their pharmacies effectively. Mobile applications providing refill prescription facilities, secure two-way messaging, HIPAA compliant mobile app will increase the customer base for online pharmacies. Vendors prioritize digital advertising and marketing to attract more audience as many patients spend their time online.

The US web-based pharmacy segment expects to reach USD 38 billion by 2026, growing at a CAGR of over 17% from 2020 to 2026. Web-based pharmacies were the first online channels for pharmacies. In the pre-mobile app era, web-based online pharmacies were used to order medicines. However, after the introduction of mobile app-based pharmacies, the demand for web-based pharmacies has reduced. There is a massive shift toward mobile app-based purchases from web-based pharmacies, thereby increasing market growth.

INSIGHTS BY PHARMACY TYPE

The U.S. epharmacy market by the online branch of brick and mortar expects to reach approx. USD 80 billion by 2026. Most retail companies in the US tend to own an online channel to promote their products and increase the customer base. This trend has been prevalent in the US for a long period. However, during the COVID-19 pandemic, the country further accelerated the adoption of online pharmacy channels.

The US independent online pharmacy market expects to reach over USD 49 billion by 2026. Independent online pharmacies have become one-stop solution providers for medical products across the US. They provide standard prescription fillings and offer several customer-friendly services, which increase their preference among customers. They offer products at high discounts as they have a unique supply chain, removing intermediaries and distributors and deliver products directly to customers. 

INSIGHTS BY VENDORS

The U.S. online pharmacy market is witnessing a steady flow of start-ups entering the industry. The COVID-19 pandemic has increased the importance of online pharmacies in the country. Many physicians, patients, and healthcare providers have increased the adoption of telehealth, which has increased the number of teleconsultations in the country. Large hospitals have received 500% more online consultations, and e-prescriptions among healthcare providers have also increased. These factors have accelerated the growth of the online pharmacy market in the US. A change in consumer behavior patterns has increased opportunities for market growth. However, strict adherence to regulatory guidelines and the prevalence of counterfeiting and fake websites selling unhealthy products are hindering the market. Kroger, CVS Health, CIGNA (Express Scripts), Walgreens Boots Alliance, and Rite Aid are the key players in the U.S. online pharmacy market.

The U.S. online pharmacy market research report includes in-depth coverage of the industry analysis, market dynamics with revenue and forecast insights for the following segments:

Drug Type

  • Prescription
  • OTC

Product

  • Medications
  • Health Wellness & Nutrition
  • Personal Care & Essentials
  • Others

Modality

  • Mobile Applications
  • Websites

Pharmacy Type

  • Online Branch of Brick & Mortar
  • Independent Online Only Pharmacies
  • Partnership Sites with Neighborhood Pharmacies

Geography

  • US

Frequently Asked Questions

Rise in direct-to-patient drug sales, increased demand for improved e-commerce technology, and the increased adoption of e-prescriptions among US customers are the key trends witnessing in the market.
The U.S. online pharmacy market expects to reach approx. USD 146 billion by 2026.
The medication segment accounted for the largest revenue share in the market.
An increase in teleconsultation and diagnostic support and growth in internet and smartphone application penetration are the significant factors influencing the US online pharmacy market.
Kroger, CVS Health, CIGNA (Express Scripts), Walgreens Boots Alliance, and Rite Aid are the key players in the market.
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The U.S. online pharmacy market by revenue is expected to grow at a CAGR of approx. 19% during the period 2020–2026.

 The following factors are likely to contribute to the growth of the U.S. online pharmacy market during the forecast period:

  • Rise in Direct to Patient Drug Sales
  • Improved E-commerce Technology driving demand
  • Increased Adoption of E-prescriptions among US Customers
  • Adoption of Automatic Prescription Refills and Automated Customer Relationship Management

Base Year:                  2020

Forecast Year:           2021–2026

The study considers the U.S. online pharmacy market's present scenario and its market dynamics for the period 2020−2026. It covers a detailed overview of several market growth enablers, restraints, and trends. The report offers both the demand and supply aspects of the market. It profiles and examines leading companies and other prominent ones operating in the market.

Prominent Vendors

  • Kroger
    • Business Overview
    • Key Strengths
    • Key Strategies
    • Key Opportunities
  • CVS Health
  • CIGNA (Express Scripts)
  • Walgreens Boots Alliance
  • Rite Aid

Other Prominent Vendors

  • Alto Pharmacy
    • Business Overview
  • Blink Health
  • BioPlus Specialty Pharmacy
  • Batell Drug
  • Carepoint Pharmacy
  • Foundation Care
  • Fruth Pharmacy
  • Giant Eagle
  • Gogomeds.com
  • Healthwarehouse
  • Hi-School Pharmacy
  • Hims & Hers Health
  • Henry Ford Health System
  • Kinney Drugs
  • KwikMed
  • MedVantx
  • Medicure
  • Medly Pharmacy
  • Northwestpharmacy.com
  • OptumRx
  • PillPack
  • Ro Pharmacy
  • Rx-24-online.com
  • Walmart Stores
  • Woori Pharmacy

Drug Type

  • Prescription
  • OTC

Product

  • Medications
  • Health Wellness & Nutrition
  • Personal Care & Essentials
  • Others

Modality

  • Mobile Applications
  • Websites

Pharmacy Type

  • Online Branch of Brick and Mortar
  • Independent Online Only Pharmacies
  • Partnerships with Neighborhood Pharmacies

Geography

  • US

1            Research Methodology

2            Research Objectives

3            Research Process

 

4            Scope & Coverage

4.1        Market Definition

4.1.1     Inclusions

4.1.2     Exclusions

4.1.3     Market Estimation Caveats

4.2        Base Year

4.3        Scope Of The Study

4.3.1     Market Segmentation By Drug Type

4.3.2     Market Segmentation by Product

4.3.3     Market Segmentation by Modality

4.3.4     Market Segmentation by Pharmacy Type

 

5            Report Assumptions & Caveats

5.1        Key Caveats

5.2        Currency Conversion

5.3        Market Derivation

 

6            Market at a Glance

7            Introduction

7.1        Overview

7.2        Impact Of COVID-19 On Us Online Pharmacy

7.3        Regulations For Online Pharmacies In US

7.4        E-Pharmacy Comparison In US Versus Global Market

7.5        Online Pharmacy Start-Ups and Their Investments

 

8            Market Opportunities & Trends

8.1        Rise In Direct-To-Patient Drug Sales

8.2        Increase In Demand For Advanced E-Commerce Technologies

8.3        High Adoption Of E-Prescriptions Among US Customers

 

9            Market Growth Enablers

9.1        Increasing Teleconsultation And Diagnostic Support

9.2        Growing Penetration Of Internet And Mobile Applications

9.3        High Adoption Of Automated Prescription Refill And CRM Solutions

 

10         Market Restraints

10.1      Sale Of Unapproved Drugs And FDA Warnings

10.2      Competition From Traditional And Medical Product Retailers

10.3      Strict Regulatory Framework For Online Sale Of Drugs

 

11         Market Landscape

11.1      Market Overview

11.2      Market Size & Forecast

11.3      Five Forces Analysis

11.3.1   Threat of New Entrants

11.3.2   Bargaining Power of Suppliers

11.3.3   Bargaining Power of Buyers

11.3.4   Threat of Substitutes

11.3.5   Competitive Rivalry

 

12         Drug Type

12.1      Market Snapshot & Growth Engine

12.2      Market Overview

12.3      Prescription

12.3.1   Market Overview

12.3.2   Market Size & Forecast

12.4      Over The Counter (OTC)

12.4.1   Market Overview

12.4.2   Market Size & Forecast

 

13         Product

13.1      Market Snapshot & Growth Engine

13.2      Market Overview

13.3      Medication

13.3.1   Market Overview

13.3.2   Market Size & Forecast

13.4      Health, Wellness, & Nutrition

13.4.1   Market Overview

13.4.2   Market Size & Forecast

13.5      Personal Care

13.5.1   Market Overview

13.5.2   Market Size & Forecast

13.6      Others

13.6.1   Market Overview

13.6.2   Market Size & Forecast

 

14         Modality

14.1      Market Snapshot & Growth Engine

14.2      Market Overview

14.3      Mobile Application

14.3.1   Market Overview

14.3.2   Market Size & Forecast

14.4      Web Based

14.4.1   Market Overview

14.4.2   Market Size & Forecast

 

15         Pharmacy Type

15.1      Market Snapshot & Growth Engine

15.2      Market Overview

15.3      Online Branch Of Brick & Mortar Pharmacy

15.3.1   Market Overview

15.3.2   Market Size & Forecast

15.4      Independent Online-Only Pharmacies

15.4.1   Market Overview

15.4.2   Market Size & Forecast

15.5      Partnership Site With Neighborhood Pharmacies

15.5.1   Market Overview

15.5.2   Market Size & Forecast

 

16         Competitive Landscape

16.1      Competition Overview

16.2      Market Share Analysis

16.2.1   CVS Health

16.2.2   Cigna (Express Scripts)

16.2.3   Walgreens Boots Alliances

16.2.4   Rite Aid

16.2.5   The Kroger

 

17         Key Company Profiles

17.1      The Kroger

17.1.1   Business Overview

17.1.2   Key Strategies

17.1.3   Key Strengths

17.1.4   Key Opportunities

17.2      CVS Health

17.2.1   Business Overview

17.2.2   Key Strategies

17.2.3   Key Strengths

17.2.4   Key Opportunities

17.3      CIGNA (Express Scripts)

17.3.1   Business Overview

17.3.2   Key Strategies

17.3.3   Key Strengths

17.3.4   Key Opportunities

17.4      Walgreens Boots Alliance

17.4.1   Business Overview

17.4.2   Key Strategies

17.4.3   Key Strengths

17.4.4   Key Opportunities

17.5      RITE AID

17.5.1   Business Overview

17.5.2   Key Strategies

17.5.3   Key Strengths

17.5.4   Key Opportunities

 

18         Other Prominent Vendors

18.1      ALTO Pharmacy

18.1.1   Business Overview

18.2      BLINK Health

18.2.1   Business Overview

18.3      Bioplus Specialty Pharma

18.3.1   Business Overview

18.4      Bartell Drugs

18.4.1   Business Overview

18.5      Carepoint

18.5.1   Business Overview

18.6      Foundation Care

18.6.1   Business Overview

18.7      Fruth Pharmacy

18.7.1   Business Overview

18.8      Giant Eagle

18.8.1   Business Overview

18.9      Gogomeds.Com

18.9.1   Business Overview

18.10    Healthwarehouse

18.10.1 Business Overview

18.11    Hi-School Pharmacy

18.11.1 Business Overview

18.12    Hims & Hers Health

18.12.1 Business Overview

18.13    Henry Ford Health System

18.13.1 Business Overview

18.14    Kinney Drugs

18.14.1 Business Overview

18.15    KWIKMED

18.15.1 Business Overview

18.16    Medvantx

18.16.1 Business Overview

18.17    Medicure

18.17.1 Business Overview

18.18    Medly Pharmacy

18.18.1 Business Overview

18.19    Northwestpharmacy.Com

18.19.1 Business Overview

18.20    Optumrx

18.20.1 Business Overview

18.21    Pillpack

18.21.1 Business Overview

18.22    RO Pharmacy

18.22.1 Business Overview

18.23    RX-24-Online.Com

18.23.1 Business Overview

18.24    Wal-Mart Stores

18.24.1 Business Overview

18.25    Woori Pharmacy

18.25.1 Business Overview

 

19         Report Summary

19.1      Key Takeaways

19.2      Strategic Recommendations

 

20         Quantitative Summary

20.1      Market By Drug Type

20.2      Market By Modality Type

20.3      Market By Product

20.4      Market By Pharmacy Type

 

21         Appendix

21.1      Abbreviations

             

 

List Of Exhibits 

Exhibit 1             Segmentation of US Online Pharmacy Market

Exhibit 2             Market Size Calculation Approach 2020

Exhibit 3             Comparison of Traditional and Online Pharmacies Distribution Channel

Exhibit 4             Rise in Direct-to-Patient Drug Sales

Exhibit 5             Increase in Demand for Advanced E-commerce Technologies

Exhibit 6             High Adoption of E-prescriptions among US Customers

Exhibit 7             EHR Adoption Rate in US (%)

Exhibit 8             Increasing Teleconsultation and Diagnostic Support

Exhibit 9             Increase in Adoption of Telemedicine Among Physicians

Exhibit 10           Growing Penetration of Internet and Mobile Applications

Exhibit 11           Internet Penetration in US 2020

Exhibit 12           High Adoption of Automated Prescription Refill and CRM Solutions

Exhibit 13           Sale of Unapproved Drugs and FDA Warnings

Exhibit 14           Illegal Online Pharmacy in US

Exhibit 15           Competition from Traditional and Medical Product Retailers

Exhibit 16           Strict Regulatory Framework for Online Sale of Drugs

Exhibit 17           Five Reasons for Consumer Shifting Online Pharmacies

Exhibit 18           Online Pharmacy Market in US 2020–2026 ($ billion)

Exhibit 19           Online Pharmacy Market in US by Drug Type

Exhibit 20           Online Pharmacy Market in US by Modality

Exhibit 21           Online Pharmacy Market in US by Product

Exhibit 22           Online Pharmacy Market in US by Pharmacy Type

Exhibit 23           Five Forces Analysis 2020

Exhibit 24           Incremental Growth by Segment 2020 & 2026

Exhibit 25           Online Pharmacy Market in US by Drug Type

Exhibit 26           Online Pharmacy Market in US by Drug Type: Incremental Growth

Exhibit 27           Online Pharmacy Market in US by Drug Type: Absolute Growth

Exhibit 28           Preference for Online Pharmacies for Prescription Medications among Consumers

Exhibit 29           US Online Pharmacy Market by Prescription: Incremental & Absolute Growth

Exhibit 30           US Online Pharmacy Market by Prescription 2020–2026 ($ billion)

Exhibit 31           Online Over the Counter Pharmacy Market in US: Incremental & Absolute Growth

Exhibit 32           Purchase Percentage of Online Pharmacy Over-the-Counter Medications in US

Exhibit 33           Online Pharmacy Over-the-Counter Market in US 2020–2026 ($ billion)

Exhibit 34           Incremental Growth by Segment  2020 & 2026

Exhibit 35           Online Pharmacy Market in the US by Product Type

Exhibit 36           Online Pharmacy Market in US by Product Type: Incremental Growth

Exhibit 37           Online Pharmacy Market in US by Product Type: Absolute Growth

Exhibit 38           US Online Pharmacy Market by Medication: Incremental & Absolute Growth

Exhibit 39           Rise in Older Population in US (millions)

Exhibit 40           Online Pharmacy Market in US by Medication 2020–2026 ($ billion)

Exhibit 41           Online Pharmacy Market in US by Health, Wellness, & Nutrition: Incremental & Absolute Growth

Exhibit 42           Online Pharmacy Market in US by Health, Wellness, & Nutrition 2020–2026 ($ billion)

Exhibit 43           Online Pharmacy Market in US by Personal Care: Incremental & Absolute Growth

Exhibit 44           Online Pharmacy Market in US by Personal Care 2020–2026 ($ billion)

Exhibit 45           Online Pharmacy Market in US by Others: Incremental & Absolute Growth

Exhibit 46           Online Pharmacy Market in US by Others 2020–2026 ($ billion)

Exhibit 47           Incremental Growth by Segment 2020 & 2026

Exhibit 48           Online Pharmacy Market in the US by Modality

Exhibit 49           Online Pharmacy Market in US by Modality: Incremental Growth

Exhibit 50           Online Pharmacy Market in US by Modality: Absolute Growth

Exhibit 51           Online Pharmacy Market in US by Mobile Application: Incremental & Absolute Growth

Exhibit 52           Online Pharmacy Market in US by Mobile Application 2020–2026 ($ billion)

Exhibit 53           Online Pharmacy Market in US by Web based: Incremental & Absolute Growth

Exhibit 54           Online Pharmacy Market in US by Web based 2020–2026 ($ billion)

Exhibit 55           Incremental Growth by Segment 2020 & 2026

Exhibit 56           Online Pharmacy Market in US by Pharmacy Type

Exhibit 57           Online Pharmacy Market in US by Pharmacy Type: Incremental Growth

Exhibit 58           Online Pharmacy Market in US by Pharmacy Type: Absolute Growth

Exhibit 59           Online Pharmacy Market in US by Online Branch of Brick & Mortar Pharmacy: Incremental & Absolute Growth

Exhibit 60           Online Pharmacy Market in US by Online branch of Brick-and-Mortar Pharmacy 2020–2026 ($ billion)

Exhibit 61           Online Pharmacy Market in US by Independent Online-Only Pharmacy: Incremental & Absolute Growth

Exhibit 62           Online Pharmacy Market in US by Independent Online-Only Pharmacy 2020–2026 ($ billion)

Exhibit 63           Online Pharmacy Market in US by Partnership Site with Neighborhood Pharmacies: Incremental & Absolute Growth

Exhibit 64           Online Pharmacy Market in US by Partnership Sites with Neighborhood Pharmacies 2020–2026 ($ billion)

Exhibit 65           Grid Representation of Online Pharmacy Vendors in US

Exhibit 66           Market Share of Tier I & Tier II Players

Exhibit 67           The Kroger Revenue 2018–2020 ($ billion)

Exhibit 68           The Kroger Revenue by Segment 2018–2020 ($ billion)

Exhibit 69           CVS Health Revenue 2018–2020 ($ billion)

Exhibit 70           CIGNA Revenue 2018–2020 ($ million)

Exhibit 71           Walgreens Boots Alliance Revenue 2018–2020 ($ million)

Exhibit 72           Rite Aid Revenue 2018–2020 ($ billion)

             

             

List of Tables    

Table 1               Key Caveats

Table 2               Currency Conversion 2013−2020

Table 3               E-pharmacy Comparison of Global versus US Market

Table 4               Funding of Online Pharmacy Start-Ups

Table 5               List of FDA Warning Letters Online Pharmacies

Table 6               Online Pharmacy Market in US by Drug Type 2020−2026 ($ billion)

Table 7               Online Pharmacy Market in US by Drug Type (%)

Table 8               Online Pharmacy Market in US by Modality 2020−2026 ($ billion)

Table 9               Online Pharmacy Market in US by Modality (%)

Table 10             Online Pharmacy Market in US by Product 2020−2026 ($ billion)

Table 11             Online Pharmacy Market in US by Product (%)

Table 12             Online Pharmacy Market in US by Pharmacy Type 2020−2026 ($ billion)

Table 13             Online Pharmacy Market in US by Pharmacy Type (%)

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